Diana Fusco



I am generally interested in the role of spatial organization in biological phenomena. In this regard, I am currently exploring how spatial structure influences evolution, specifically regarding the emergence of drug resistance. To tackle this problem, I use a combination of population genetics theory, computer simulations, and microbiology experiments.


  • 2014: Postdoc with Oskar Hallatschek, University of California, Berkeley
  • 2008-2014: PhD in Computational Biology and Bioinformatics from Duke University, Durham, NC
  • 2006-2008: MSc in Theoretical Physics from University of Milan, Milan, Italy
  • 2003-2006: BSc in Physics from University of Milan, Milan, Italy

Selected publications:

Fusco, D., Gralka M., Kayser J., Anderson A., & Hallatschek O. (2016) Excess of mutational jackpot events in expanding populations revealed by spatial Luria-Delbrück experiments. Nature Communications 7:12760.

Fusco, D., & Charbonneau, P. (2014). Competition between monomeric and dimeric crystals in schematic models for globular proteins. The Journal of Physical Chemistry B 118(29):8034-8041.

Fusco, D., Headd, J. J., De Simone, A., Wang, J., & Charbonneau, P. (2014). Characterizing protein crystal contacts and their role in crystallization: rubredoxin as a case study. Soft matter, 10(2): 290-302.

Fusco, D., & Charbonneau, P. (2013). Crystallization of asymmetric patchy models for globular proteins in solution. Physical Review E, 88(1): 012721.

Fusco, D., & Uyenoyama, M. K. (2011). Sex-specific incompatibility generates locus-specific rates of introgression between species. Genetics, 189(1): 267-288.